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An overview of Amblyopia

What is Amblyopia?

Amblyopia (also called lazy eye) is a type of poor vision that usually happens in just 1 eye but less commonly in both eyes. It develops when there’s a breakdown in how the brain and the eye work together, and the brain can’t recognize the sight from 1 eye. Over time, the brain relies more and more on the other, stronger eye — while vision in the weaker eye gets worse.

It’s called “lazy eye” because the stronger eye works better. But people with amblyopia are not lazy, and they can’t control the way their eyes work.

Amblyopia starts in childhood, and it’s the most common cause of vision loss in kids. Up to 3 out of 100 children have it. The good news is that early treatment works well and usually prevents long-term vision problems.

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Is my child at risk for Amblyopia?

Some kids are born with amblyopia and others develop it later in childhood. The chances of having amblyopia are higher in kids who:

1. Were born early (premature)

2. Were smaller than average at birth

3. Have a family history of amblyopia, childhood cataracts, or other eye conditions

4. Have developmental disabilities

Causes of Amblyopia

In many cases, doctors don’t know the cause of amblyopia. But sometimes, a different vision problem can lead to amblyopia.

Normally, the brain uses nerve signals from both eyes to see. But if an eye condition makes vision in 1 eye worse, the brain may try to work around it. It starts to “turn off” signals from the weaker eye and rely only on the stronger eye.

Some eye conditions that can lead to amblyopia are:

1. Refractive errors. These include common vision problems like nearsightedness (having trouble seeing far away), farsightedness (having trouble seeing things up close), and astigmatism (which can cause blurry vision). Normally, these problems are easy to fix with glasses or contacts. But if they’re not treated, the brain may start to rely more on the eye with stronger vision.

2. Strabismus. Usually, the eyes move together as a pair. But in kids with strabismus, the eyes don’t line up. One eye might drift in, out, up, or down.

3. Cataract. This causes cloudiness in the lens of the eye, making things look blurry. While most cataracts happen in older people, babies and children can also develop cataracts.

Signs and symptoms of Amblyopia

Symptoms of amblyopia can be hard to notice. Kids with amblyopia may have poor depth perception — they have trouble telling how near or far something is. Parents may also notice signs that their child is struggling to see clearly, like:

1. Squinting

2. Shutting 1 eye

3. Tilting their head

In many cases, parents don’t know their child has amblyopia until a doctor diagnoses it during an eye exam. That’s why it’s important for all kids to get a vision screening at least once between ages 3 and 5.

Preventive measures against Amblyopia

The number one way to prevent amblyopia is through regular checkups with an eye care professional, says Williamson.

Limiting screen time for children may help prevent amblyopia, she says. “There’s a growing body of evidence describing the negative effects of screens on children’s vision. This generation isn’t running around outside and playing as much as previous generations — they are using smartphones and tablets much more,” says Williamson.

Research out of Ireland found that using screens for more than three hours a day increased the odds of myopia (nearsightedness) in schoolchildren.Severe myopia may put children at risk for eye problems later in life, including retinal detachment, glaucoma, and macular degeneration.

Practice good visual habits, which include avoiding touching the eyes or eye rubbing, she suggests. “If your child is doing one or both of these, bring them in so we can figure out why and, if necessary, treat it,” says Williamson.

Everything doctors recommend for your overall health is also going to be good for your eyes, she says. “That includes eating lots of fruit and vegetables, regular exercise, and drinking enough water,” says Williamson.

Nutrients, including zinc, lutein, omega-3 fatty acids, and the vitamins A, C, and E, have been found to be beneficial to eye health. Oranges, strawberries, and mangoes have vitamins C and E, which can help restore tissues and prevent infections.

How Is Amblyopia Diagnosed?

As part of a normal vision screening, your child’s doctor will look for signs of amblyopia.

All kids ages 3 to 5 need to have their vision checked at least once.

Treatment for Amblyopia

If there’s a vision problem causing amblyopia, the doctor may treat that first. For example, doctors may recommend glasses or contacts (for kids who are nearsighted or farsighted) or surgery (for kids with cataract).

The next step is to re-train the brain and force it to use the weaker eye. The more the brain uses it, the stronger it gets. Treatments include:

Wearing an eye patch on the stronger eye. By covering up this eye with a stick-on eye patch (similar to a Band-Aid), the brain has to use the weaker eye to see. Some kids only need to wear the patch for 2 hours a day, while others may need to wear it whenever they're awake.

Putting special eye drops in the stronger eye. A once-a-day drop of the drug atropine can temporarily blur near vision, which forces the brain to use the other eye. For some kids, this treatment works as well as an eye patch, and some parents find it easier to use (for example, because young children may try to pull off eye patches).

After your child starts treatment, their vision may start to get better within a few weeks. But it will probably take months to get the best results. After that, your child may still need to use these treatments from time to time to stop amblyopia from coming back.

It’s important to start treating children with amblyopia early — the sooner the better. Kids who grow up without treatment may have lifelong vision problems. Amblyopia treatment is usually less effective in adults than in children.

Complications

If amblyopia isn’t treated early enough, it can result in a permanent visual defect or loss of depth perception. If, later in life, the “good” eye ever gets diseased or injured, a person may have to live the rest of their life with poor vision.

Frequently Asked Questions About Amblyopia

One of the most common questions about lazy eye is what causes it. Lazy eye occurs when one eye does not work in coordination with the brain resulting in poor vision quality. This causes the brain to favor the other eye with better visual quality. Without treatment, the amblyopic or ‘lazy’ eye can wander, causing it to drift to either side, upward, or downward.
Refractive amblyopia on the other hand typically doesn’t cause the eye to wander, and even though one eye can see better than the other, they remain aligned symmetrically.

Lazy Eye vs Crossed Eyes
While amblyopia may cause one eye to wander and appear ‘lazy’, strabismus is a different condition that causes both eyes to point in different directions causing a ‘cross-eyed’ appearance. While one eye may sometimes point straight ahead, both eyes will never align in the same direction, and the misalignment can shift from eye to eye.

Lazy eye generally develops in children between birth and the age of seven. When we are born, our eyes take time to adapt and learn how to properly focus light, movements, and colors. When a child has amblyopia, one eye is used far more efficiently than the other, which results in the weaker or ‘lazy’ eye developing poor vision quality.

The only way to diagnose amblyopia is through comprehensive vision testing performed by an ophthalmologist. Through a variety of non-invasive tests, your eye doctor will be able to detect any differences in visual quality between the eyes.

For young children, getting a precise measurement of their vision can be challenging. So your ophthalmologist will cover one eye at a time and watch how well the child follows objects with each eye to get an estimate of their visual acuity.

These tests are not painful, but if a child does have an amblyopic eye they may cry or become distressed when their stronger eye is covered. Suddenly not being able to see clearly would be distressing for anyone.

Unfortunately, 25% of people who have amblyopia at a young age, develop the condition again later on in life. This makes it incredibly important for anyone who has ever been diagnosed with an eye condition to attend routine eyes exams to ensure optimal vision health

Currently, there is no surgical option for treating lazy eye. The idea of a ‘lazy eye surgery’ is a common misconception that usually comes from the confusion between strabismus (crossed-eyes) and amblyopia (lazy eye). Strabismus surgery involves repositioning the eye muscles to help the eyes point in the same direction.

However, in cases where a cataract causes a patient to develop a lazy eye, surgery to remove the clouded lens can result in amblyopia being corrected as well.

Depending on the severity, treatment can last anywhere from a couple of months to two years. With proper treatment, most patients will begin to see vision improvements within a few weeks to months.

It’s important to continue to follow all treatment instructions provided by your doctor, even with positive improvements in vision quality.